Environmental stresses induce karyotypic instability in colorectal cancer cells
نویسندگان
چکیده
منابع مشابه
Regulatory T Cells in Colorectal Cancer
One of the essential protection mechanisms of immune system is Treg cells which play an important role in maintenance ofimmune homeostasis. However, they may also inhibit immune functions against tumor cells. It has been reported that Treg cellsare increased in patients suffering from different types of cancer. Increased number of Treg cells has been shown in tumor lymphnodes, peripheral blood,...
متن کاملgenomic and epigenetic instability in colorectal cancer
abstract: colorectal cancer (crc) is the third most common cancer in men and the second most common cancer in women worldwide. both genetic and epigenetic alterations are common in crc and are the driving force of tumorigenesis. chromosomal instability, microsatellite instability and cpg island methylator phenotype pathways are responsible for genetic instability in colorectal cancer. chromosom...
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Misfolded protein aggregation in mammalian cells is one of the cellular responses to environmental stresses. However, the aggregation of misfolded proteins in plant cells exposed to environmental stresses is still poorly understood. Here, we report the misfolded protein aggregation in plant cells in response to environmental stresses, including ultraviolet (UV) radiation, heat stress and cold s...
متن کاملGenetic instability in colorectal cancer.
The development of neoplasia has been thought to be associated with genetic alterations for many years. In colorectal cancer two specific types of genetic instability have been defined. One is associated with chromosomal instability and the other with DNA microsatellite instability, also known as replication errors. The mechanism underlying tumorigenesis leads to profound diVerences in the path...
متن کاملGenetic instability in colorectal cancer
The development of neoplasia has been thought to be associated with genetic alterations for many years. In colorectal cancer two specific types of genetic instability have been defined. One is associated with chromosomal instability and the other with DNA microsatellite instability, also known as replication errors. The mechanism underlying tumorigenesis leads to profound diVerences in the path...
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ژورنال
عنوان ژورنال: Molecular Biology of the Cell
سال: 2019
ISSN: 1059-1524,1939-4586
DOI: 10.1091/mbc.e18-10-0626